Thermal water is said to be effective for the waist ache, rheumatism, sciatica, nephrite, backache, dermal problems and gynecological diseases treatments 

21 days of treatment is applied in the thermal spring and at first, two times of bathing, 10 minutes each, is required. Additionally, when it is used as drinking water, it is good for liver, gall bladder and bowel problems.

Water in Sultaniye Thermal Spring was started to be used in the time of Kaunos people. Later, accommodation places were built by Byzantine people. Dock and building ruins from this period of time are under the water of Köyceğiz Lake.